Publicações recentes (selecionadas)

Whole-exome sequencing and copy number alterations analysis in a case of expansive florid cemento-osseous dysplasia. Gomes CC, Bastos VC, El Mouatani A, Duarte-Andrade FF, Jabado N, de Castro WH, Gomez RS.Clin Case Rep. 2024 Aug 5;12(8):e9265. doi: 10.1002/ccr3.9265. eCollection 2024. PMID: 39109314

The evolving molecular characterisation, histological criteria and nomenclature of adenoid ameloblastoma as a World Health Organisation tumour type.  Odell EW, Gomes CC, Thavaraj S.Histopathology. 2024 Dec;85(6):846-852. doi: 10.1111/his.15270.PMID: 38922981

Comprehensive Genomic Analysis of Cemento-Ossifying Fibroma. Gomez RS, El Mouatani A, Duarte-Andrade FF, Pereira TDSF, Guimarães LM, Gayden T, Faury D, Nakada EM, Langlois S, Sinnett D, de Castro WH, Diniz MG, Jabado N, Gomes CC. Mod Pathol. 2024 Feb;37(2):100388. doi: 10.1016/j.modpat.2023.100388. Epub 2023 Nov 22.PMID: 37995913

DNA methylation profile discriminates sporadic giant cell granulomas of the jaws and cherubism from their giant cell-rich histological mimics. Guimarães LM, Baumhoer D, Andrei V, Friedel D, Koelsche C, Gomez RS, von Deimling A, Gomes CC.J Pathol Clin Res. 2023;9(6):464-474. doi: 10.1002/cjp2.337.PMID: 37555357                                          

Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration. Khazaei S, Chen CCL, Andrade AF, Kabir N, Azarafshar P, Morcos SM, França JA, Lopes M, Lund PJ, Danieau G, Worme S, Adnani L, Nzirorera N, Chen X, Yogarajah G, Russo C, Zeinieh M, Wong CJ, Bryant L, Hébert S, Tong B, Sihota TS, Faury D, Puligandla E, Jawhar W, Sandy V, Cowan M, Nakada EM, Jerome-Majewska LA, Ellezam B, Gomes CC, Denecke J, Lessel D, McDonald MT, Pizoli CE, Taylor K, Cocanougher BT, Bhoj EJ, Gingras AC, Garcia BA, Lu C, Campos EI, Kleinman CL, Garzia L, Jabado N.Cell. 2023,16;186(6):1162-1178.e20. doi: 10.1016/j.cell.2023.02.023.PMID: 36931244 

No NFATC2 fusion in simple bone cyst of the jaw. Ong SLM, Gomes IP, Baelde HJ, Passador-Santos F, de Andrade BAB, Briaire-de Bruijn IH, Cavalcante IL, Schreuder WH, Cleton-Jansen AM, Cleven AHG, Szuhai K, Gomes CC, Bovée JVMG.Histopathology. 2023 Aug;83(2):326-329. doi: 10.1111/his.14905.PMID: 36939112

Adenoid ameloblastoma harbors beta-catenin mutations. Bastos VC, Coura BP, Guimarães LM, Fernandes BG, Chan AC, Vargas PA, Bastos-Rodrigues L, De Marco LA, Hellstein J, Thavaraj S, Wright JM, Odell EW, Gomez RS, Gomes CC.Mod Pathol. 2022 Nov;35(11):1562-1569. doi: 10.1038/s41379-022-01125-4. PMID: 35840721 

Making sense of giant cell lesions of the jaws (GCLJ): lessons learned from next-generation sequencing. Gomes CC, Diniz MG, Bastos VC, Bernardes VF, Gomez RS. J Pathol. 2020 Feb;250(2):126-133. doi: 10.1002/path.5365.

Assessing pathogenic mutations in dental follicles as an attempt to identify early events in odontogenic tumours tumourigenesis. Coura BP, de Resende TAC, de Menezes VCB, Bernardes VF, de Sousa SF, Diniz MG, Gomez RS, Gomes CC. Arch Oral Biol. 2020 May;113:104523. doi: 10.1016/j.archoralbio.2019.104523.

First insights for targeted therapies in odontogenic myxoma. Pereira NB, Bastos VC, de Souza JC, Diniz MG, Vitório JG, Kitten GT, de Oliveira Andrade L, de Avelar GF, Castro WH, Bernardes VF, Dias AAM, Gomez RS, Gomes CC. Clin Oral Investig. 2020;24(7):2451-2458. doi: 10.1007/s00784-019-03107-4.

Cherubism: a systematic literature review of clinical and molecular aspects. Chrcanovic BR, Guimarães LM, Gomes CC, Gomez RS. Int J Oral Maxillofac Surg. 2020;30:S0901-5027(20)30213-7. doi: 10.1016/j.ijom.2020.05.021.

KRAS mutations in brown tumor of the jaws in hyperparathyroidism. Guimarães LM, Gomes IP, Pereira TDSF, de Andrade BAB, Romañach MJ, de Lacerda JCT, Pontes HAR, Brennan PA, Rahimi S, Carlos R, Mosqueda-Taylor A, Bologna-Molina R, Passador-Santos F, Gomez RS, Gomes CC. J Oral Pathol Med. 2020. doi: 10.1111/jop.13048.

KRAS mutations drive adenomatoid odontogenic tumor and are independent of clinicopathological features. Coura BP, Bernardes VF, de Sousa SF, França JA, Pereira NB, Pontes HAR, Batista AC, da Cruz Perez DE, Albuquerque Junior RLC, de Souza LB, Martins MD, Diniz MG, Gomez RS, Gomes CC. Mod Pathol. 2019 Jun;32(6):799-806. doi: 10.1038/s41379-018-0194-4.

TRPV4 and KRAS and FGFR1 gain-of-function mutations drive giant cell lesions of the jaw. Gomes CC, Gayden T, Bajic A, Harraz OF, Pratt J, Nikbakht H, Bareke E, Diniz MG, Castro WH, St-Onge P, Sinnett D, Han H, Rivera B, Mikael LG, De Jay N, Kleinman CL, Valera ET, Bassenden AV, Berghuis AM, Majewski J, Nelson MT, Gomez RS, Jabado N. Nat Commun. 2018;9(1):4572. doi: 10.1038/s41467-018-06690-4.